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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T61448 | AZA1 | Rac1/Cdc42-IN-1 | Apoptosis , Rho , CDK |
AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42. AZA1 induced apoptosis of prostate cancer cells and inhibited cell proliferation, migration and invasion. | |||
T6864 | Ixabepilone | BMS 247550,Ixempra,Azaepothilone B,BMS 247550-1 | Apoptosis , Microtubule Associated |
Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell ... | |||
T29254 | MK-0963 | ||
(5Alpha)-23-methyl-4-aza-21-norchol-1-ene-3,20-dione is a bioactive chemical. | |||
TNU0304 | 1-(b-D-Xylofuranosyl)-6-azauracil | ||
1-(b-D-Xylofuranosyl)-6-azauracil is a Nucleoside Derivative - Xylo-nucleoside; 6-Aza-uridine. | |||
TNU0389 | 6-Amino-3-ethynyl-4-methoxy-1-(b-D-ribofuranosyl)-1H- pyrazolo[3,4-d]pyrimidine | ||
6-Amino-3-ethynyl-4-methoxy-1-(b-D-ribofuranosyl)-1H- pyrazolo[3,4-d]pyrimidine is a Nucleoside Derivative - 8-Aza-7-deaza-purine nucleoside; 6-Modified purine nucleoside. | |||
TNU0390 | 6-Amino-3-(furan-2-yl)-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine | ||
6-Amino-3-(furan-2-yl)-4-methoxy-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a Nucleoside Derivative - 8-Aza-7-deaza-purine nucleoside; 6-Modified purine nucleoside. | |||
TNU1035 | 3,6-Dibromo-1,5-dihydro-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one | ||
3,6-Dibromo-1,5-dihydro-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one is a Nucleoside Derivative - 7-Deaza-8-aza-purine nucleoside; Halo-nucleoside; Scaffold and Template. | |||
T83296 | 5-Azacytidine 5′-triphosphate | ||
5-Azacytidine 5′-triphosphate (5-aza-CMP), a cytidine analog, selectively inhibits the incorporation of [^3H]CTP into RNA during the DNA-dependent RNA polymerase reaction, while not affecting the incorporation of [^3H]UT... | |||
T75082 | 2-Amino-8-aza-7-deaza-7-iodoguanosine | ||
2-Amino-8-aza-7-deaza-7-iodoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibit... | |||
T37983 | GM 1489 | ||
GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively. It reduces 5-aza-2'-deoxycytidine-induc... | |||
T75220 | 5-Aza-xylo-cytidine | ||
5-Azacitidine, a purine nucleoside analog, exhibits wide-ranging antitumor efficacy against indolent lymphoid malignancies by inhibiting DNA synthesis and inducing apoptosis, among other mechanisms [1]. | |||
T36440 | GS-441524 tris-isobutyryl ester | ||
GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with... |